Dermatophytes

Convenor(s):

Michael Arabatzis (marabatz@med.uoa.gr)
Yvonne Graeser (yvonne.graeser@charite.de)
Vit Hubka

 

Overview

The objectives of the working group are:

  • To work towards forming a consensus on standard PCR-based diagnostic methodology, able to complement or even replace the current standard in dermatophyte diagnosis, direct microscopy and culture. 
  • To bring together clinicians, scientists, veterinarians, laboratorians and others united by their common interests on dermatophyte diagnosis and other diverse aspects of dermatophyte science.
  • To motivate young scientists (i.e. molecular biologists, taxonomists, etc) working in mycology to join dermatophyte research and motivate clinicians to incorporate scientific advances in their work.
  • To build a database with dermatophyte sequences, representing the global dermatophyte variability. This database could work complementary to other similar databases (e.g. the CBS dermatophyte database).
  • As a secondary aim, to start registering the contemporary geographic distribution of the various dermatophyte species and strains, thus paving the way for a future systematic work on global epidemiology.
  • To preserve dermatophyte strains (in international Culture Collections, eg. CBS etc.), make them available to the international scientific community, thus encouraging further research.
  • To form a platform for the free exchange of ideas on the topic.

Achievements

  1. Organisation of a workshop session “Dermatological infections” at the 19th ISHAM Congress 2015 in Melbourne.
  2. The group was represented in EADV Congress Vienna 2016 by one of the coordinatorsm who presented on "Mycotic infections of the scalp"
  3. The working group has been responsible for a number of publications (see below) and presentations, including an ISHAM Workshop from 29-30th October,  2016 on Developments in fundamental and clinical aspects of dermatophytes” held at the CBS in Utrecht, Netherlands. 
  4. In 2015, a proficiency test (external quality control for diagnostic routine laboratories) was developed for the “genome detection of dermatophytes”. This test is offered by Instand e.V. twice a year. 

Publications

GS de Hoog, K Dukik, M Monod, A Packeu, D Stubbe, M Hendrickx, C Kupsch, JB Stielow, J Freeke, M Göker, A Rezaei-Matehkolaei, H Mirhendi, Y Gräser.  Toward a Novel Multilocus Phylogenetic Taxonomy for the Dermatophytes. Mycopathologia (2017) 182 (1) 5-31 (Link here to the article)

C. Kupsch, T Ohst, F Pankewitz, P Nenoff, S Uhrlass, I Winter, Y Graser. The agony of choice in dermatophyte diagnostics—performance of different molecular tests and culture in the detection of Trichophyton rubrum and Trichophyton interdigitale. Clin Microbiol Infect. 2016;22(8):735.e11–735.e17 (Link here to the article)